A Brainstem Plus Sign in Neuro-Behcet Disease

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A brainstem plus sign in neuro-Behçet disease.

Picture 1. (A-F) Axial FLAIR brain MRI revealed multiple hyperintense lesions involving bilateral pontomedular junctions, right-sided midbrain, thalamus and gangliocapsular area. This finding of confluent brainstem lesions extending into unilateral thalamus and basal ganglia is so-caled “brainstem plus”sign. (G) Lesions were isointense on T1-weighted image. (H) T1-weighted axial MRI with gadoli...

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Behcet disease is a rare multi-system immune related vasculitis which may involve the central nervous system, usually during the course of the illness. Magnetic resonance imaging is currently the modality of choice for the detection of the parenchymal lesions in their different phases, as well as the dural sinus venous thrombosis.

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Role of diffusion-weighted MRI in Neuro-Behcet`s disease.

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[Behcet disease].

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Behçet disease is a multisystem disease of unknown cause in which an inflammatory perivasculitis can arise in almost any tissue (Sakane et al., 1999). Neurologic involvement in Behçet disease was first reported by Knapp in 1941. It represented between 4-49% of manifestations of BD (Haghighi et al., 2005). There is one of the most serious causes of long term morbidity and mortality in Behçet’s D...

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2009

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.48.2399